MGMPRC is poised to serve regulatory services for the industrial and R&D needs of industries and researchers in both public and private sectors across the globe. MGMPRC’s extended research support includes end-to-end delivery of the program by providing consultancy, study designs, and the conduct of studies, as well as providing a scientific rationale for the findings of the study.

Fish Embryo Acute Test (FET)

3Rs - aligned method for fast and high throughput acute toxicity assessment in vivo.

The Fish Embryo Acute Test rapidly assesses chemical toxicity in vivo, providing quick high-throughput screening with predictive accuracy akin to adult fish models. It reduces reliance on animal testing, aligning with ethical standards and enhancing efficiency in research and development.

It is described in the OECD 236 Guideline as a test required for ecotoxicological regulatory purposes, and it is also useful to assess the safety of compounds in preclinical research.


  1. High experimental throughput for chemical safety assessment in vivo.
  2. Convenient drug delivery.
  3. Cost-efficiency.
  4. Highly predictive for acute toxicity effects in humans.
  5. Alternative experimental method to reduce animal testing while evaluating toxicity in vivo.
  6. Applicable to a wide range of compounds regardless of the mode of action, volatility, solubility, and hydrophobicity.

We'd like to hear from you

If you want more information about our FET assay or have any other questions, please contact us.

Dr.Rakesh Sharma M PhD
Research associate
SBV (Deemed to be University)
Pondicherry- 607402
[email protected]
Mobile: +91 9790080456